Feb 2002 Vol. 1 No. 1
Ethylene Glycol (Antifreeze) Ingestion
Ethylene glycol (C2H6O2, CAS # 107-21-1) is a significant cause of poisoning morbidity and mortality in California. Ethylene glycol (EG) per se causes an altered mental status similar to ethyl alcohol. More importantly,
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Jun 2002 Vol. 1 No. 2
The Anthrax Outbreak of 2001,
Lessons Learned in California
It has been more than six months since the last case of human anthrax attributed
to the release of B. anthracis spore contaminated letters in the eastern United
States. Although |
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Feb 2003 Vol. 1 No. 3
Diagnosis and Treatment of
Pediatric Iron Ingestion
Iron is essential for normal tissue and organ function. In toxic doses, iron
salts (ferrous sulfate, fumarate or gluconate) cause corrosive gastrointestinal
effects followed by hypotension, metabolic acidosis, and multisystem failure. |
Jun 2003 Vol. 1 No. 4
Whole Bowel Irrigation
The rationale behind GI decontamination
is to prevent absorption of ingested toxins by either
eliminating the toxin from the GI tract or binding the
toxin within the GI tract.
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Sept 2003 Vol. 1 No. 5
Carbon Monoxide Poisoning
Carbon monoxide (CO) poisoning remains an important cause of illness and death. A colorless, odorless gas produced by the combustion of any organic material, it has been implicated in approximately 5,000 deaths per year in the United States.
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Nov 2003 * No. 6
Lithium Toxicity
The medical use of lithium has evolved considerably since it was first used for gout and rheumatism in the 1800’s. It was also used as a salt substitute in patients with hypertension, and was at one point present in the soft drink...
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Drug-Induced QT Prolongation
The “long QT syndrome” is characterized by a long QT interval on electrocardiogram and symptoms such as syncope or even cardiac arrest due to the development of...
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May 2004 Vol. 2 No. 2
Loxoscelophobia: The
Alleged Brown Recluse Spider Bite
Loxosceles reclusa, or the brown recluse spider is one of the most feared and at the same time misunderstood arthropods in...
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Nov 2004 Vol. 2 No. 3
Physostigmine
Physostigmine is a reversible acetylcholinesterase inhibitor capable of temporarily reversing the effects of antimuscarinic agents. It was first derived from a plant in Africa,...
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Dec 2004 Vol. 2 No. 4
Management
of Sulfonylurea Overdose
There are multiple oral agents available for the treatment of diabetes. These include several pharmacological classes: the sulfonylureas, biguanides, a-glucosidase inhibitors, thiolidinediones, and ...
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April 2005 Vol. 3 No. 1
Calcium channel blocker Toxicity
Calcium channel blockers (CCB) are used extensively
for treatment of hypertension, angina pectoris, tachyarrhythmias and migraine
prophylaxis. Reports of serious CCB...
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April 2005 Vol. 3 No. 2
Nicotine Poisoning
Nicotine is a water-soluble alkaloid found primarily in plants of the Nicotiana species, although it is also found in lower quantities in... |
April 2005 Vol. 3 No. 3
Poisoning-related Hypotension
Hypotension is a frequently encountered problem in patients with poisoning or drug overdose. Toxicological causes of hypotension are... |
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April 2005 Vol. 3 No. 4
Diagnosis and Treatment of
Acute Isoniazid Poisoning
Isoniazid (INH, isonicotinic hydrazide) is a synthetic derivative of nicotinamide (vitamin B3). It has been used for over 50 years in... |
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April 2006 Vol. 4 No. 1
Using Activated Charcoal
In Medical Toxicology
Activated charcoal is the single most widely used method of gastrointestinal (GI) decontamination for the treatment of... |
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